Cannabidiol (CBD) is often covered in the media, and you may
see it touted as an add-in booster to your post-workout smoothie or morning
coffee. You can even buy a CBD-infused sports bra. But what exactly is CBD? And
why is it so popular?
How is cannabidiol
different from marijuana, cannabis and hemp?
CBD, or cannabidiol, is the second most prevalent active
ingredient in cannabis (marijuana). While CBD is an essential component of
medical marijuana, it is derived directly from the hemp plant, a cousin of
marijuana, or manufactured in a laboratory. One of hundreds of components in
marijuana, CBD does not cause a "high" by itself. According to a
report from the World Health Organization, "In humans, CBD exhibits no
effects indicative of any abuse or dependence potential…. To date, there is no
evidence of public health related problems associated with the use of pure
CBD."
Is cannabidiol legal?
CBD is readily obtainable in most parts of the United
States, though its exact legal status has been in flux. All 50 states have laws
legalizing CBD with varying degrees of restriction. In December 2015, the FDA
eased the regulatory requirements to allow researchers to conduct CBD trials.
In 2018, the Farm Bill made hemp legal in the United States, making it
virtually impossible to keep CBD illegal – that would be like making oranges
legal, but keeping orange juice illegal.
The evidence for
cannabidiol health benefits
CBD has been touted for a wide variety of health issues, but
the strongest scientific evidence is for its effectiveness in treating some of
the cruelest childhood epilepsy syndromes, such as Dravet syndrome and
Lennox-Gastaut syndrome (LGS), which typically don’t respond to antiseizure
medications. In numerous studies, CBD was able to reduce the number of
seizures, and, in some cases, stop them altogether. Epidiolex, which contains
CBD, is the first cannabis-derived medicine approved by the FDA for these conditions.
Is CBD safe?
Side effects of CBD include nausea, fatigue and
irritability. CBD can increase the level of blood thinning and other medicines
in your blood by competing for the liver enzymes that break down these drugs.
Grapefruit has a similar effect with certain medicines. People taking high
doses of CBD may show abnormalities in liver related blood tests. Many
non-prescription drugs, such as acetaminophen (Tylenol), have this same effect.
So, you should let your doctor know if you are regularly using CBD.
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